Potential of Neuroprotective Antioxidant-b Peltophorum Africanum Sond.(fabaceae)

نویسندگان

  • E. S. Bizimenyera
  • M. A. Aderogba
چکیده

There is ample scientific and empirical evidence supporti the control of neurodegenerative disorders. Antioxidants may have neuroregenerative roles, by reducing or reversing cellular damage a loss. Although demand for phytotherapeutic agents is growing, there plant–derived extracts gain wider acceptance and use. We have eva africanum (weeping wattle), a plant widespread in the tropics and t acute and chronic pain, anxiety and depression. The dried leaves, b with acetone. Thin layer chromatograms were sprayed with 0.2% methanol for screening for antioxidants. Quantification of antioxida 2, 5,7,8-tetramethylchromane-2-carboxylic acid (Trolox) and L-asco two free radicals, 2,2 ́-azinobis (3-ethyl-benzothiazoline-6-sulfon Results of our study show that the bark and root extracts had high and Trolox, a synthetic vitamin-E analogue. The respective TEAC values for the bark and root extracts, and Trolox were 1.08, 1.28 an μg/mL) was more active than the leaf 6.54 (μg/mL), but much less (3.82 μg/mL) extracts. Continued work on P. africanum, and ot neuroscientists with potent neuroprotective antioxidant therapeutics.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Potential of neuroprotective antioxidant-based therapeutics from Peltophorum africanum Sond. (Fabaceae).

There is ample scientific and empirical evidence supporting the use of plant-derived antioxidants for the control of neurodegenerative disorders. Antioxidants may have neuroprotective (preventing apoptosis) and neuroregenerative roles, by reducing or reversing cellular damage and by slowing progression of neuronal cell loss. Although demand for phytotherapeutic agents is growing, there is need ...

متن کامل

In-vitro assessment of the antiproliferative and apoptotic potential of the ethyl acetate extract of Peltophorum africanum on different cancer cell lines

We evaluated the in vitro antiproliferative and apoptotic potential of the ethyl acetate extract (EAE) of Peltophorum africanum, a member of the family Fabaceae (Sond) in order to validate its pharmacological use. Antiproliferation of human breast (MCF-7), colon (HT-29) and cervical (HeLa) cancer cell lines by EAE was investigated using the Cell Titer-Blue viability assay and the mechanism of a...

متن کامل

In-vitro assessment of the antiproliferative and apoptotic potential of the ethyl acetate extract of Peltophorum africanum on different cancer cell lines

We evaluated the in vitro antiproliferative and apoptotic potential of the ethyl acetate extract (EAE) of Peltophorum africanum, a member of the family Fabaceae (Sond) in order to validate its pharmacological use. Antiproliferation of human breast (MCF-7), colon (HT-29) and cervical (HeLa) cancer cell lines by EAE was investigated using the Cell Titer-Blue viability assay and the mechanism of a...

متن کامل

In - vitro Assessment of the Antiproliferative and Apoptotic Potential of the Ethyl acetate Extract of Peltophorum africanum on Different Cancer Cell Lines

We evaluated the in-vitro antiproliferative and apoptotic potential of the ethyl acetate extract (EAE) of Peltophorum africanum, a member of the family Fabaceae (Sond) in order to validate its pharmacological use. Antiproliferation of human breast (MCF-7), colon (HT-29) and cervical (HeLa) cancer cell lines by EAE was investigated using the Cell Titer-Blue viability assay and the mechanism of a...

متن کامل

In Vitro Activity of Peltophorum Africanum Sond. (fabacae) Extracts on the Egg Hatching and Larval Development of the Parasitic

Trichostrongylus colubriformis is an important cause of parasitic gastroenteritis in ruminants, where it causes protracted diarrhoea, rapid loss of weight, loss of production and death. The in vitro efficacy of extracts of Peltophorum africanum was determined against this parasitic nematode. Eggs and larvae of T. colubriformis were incubated at 23oC in the extracts of the leaf, bark and root of...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2006